Hypoxic glove boxes are specialised laboratory enclosures designed to create and maintain a low-oxygen environment, which is crucial for working with oxygen-sensitive materials. These glove boxes enable researchers to handle samples that may be reactive or unstable in the presence of oxygen, thus preserving their integrity and ensuring accurate experimental results. Equipped with built-in gloves, these boxes allow users to manipulate materials without direct exposure, minimising contamination risks. Hypoxic glove boxes often utilise gas control systems to monitor and adjust oxygen levels while maintaining inert atmospheres, typically using nitrogen or argon. They are widely used in fields such as biochemistry, molecular biology, and materials science, where controlled conditions are essential for studying cellular processes, synthesising new compounds, or conducting sensitive reactions.