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Case Study: Investigating Bladder Cancer in Scottish Terriers

Scottish Terriers and Bladder Cancer Risk

Scottish Terriers are up to twenty times more likely than other breeds to develop a type of bladder cancer known as transitional cell carcinoma (TCC). The reason behind this significantly increased risk remains unknown, and sadly, it can affect dogs from a relatively young age.

To address this, A/Prof Antonia Pritchard and Dr Colette Mustard have secured research funding to investigate the underlying causes of this condition. They are working in collaboration with Dr Simon Bate, a veterinary oncologist at Scottish Vet Referrals on Inverness Campus.

Understanding the Genetic Risk in Scottish Terriers

A key focus of this study is to explore whether there are genetic factors that predispose Scottish Terriers to bladder cancer. Researchers will collect buccal (cheek) swabs from participating Scotties, which will allow DNA testing to identify potential genetic markers linked to TCC.

Towards Early Detection of Canine Bladder Cancer

The team is also examining possible early markers of disease. By analysing urine samples, they hope to detect biological indicators of bladder cancer before clinical symptoms develop. This research could pave the way for a simple, non-invasive test that Scottish Terrier owners can use at home. Early detection is crucial: the sooner cancer is identified and treatment begins, the better the long-term outcome for affected dogs.

Why This Research Matters

Bladder cancer in dogs, particularly TCC in Scottish Terriers, is a growing concern for owners and veterinary professionals alike. This pioneering research not only seeks to improve understanding of the disease in Scotties but could also help inform wider canine cancer research. Ultimately, the findings may lead to earlier diagnosis, more effective treatments, and improved quality of life for affected pets.

đź”— Read more about the project on the University of the Highlands and Islands website


A person in a lab coat holding a test tube

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(Dr Colette Mustard using the Hettich Universal Benchtop 320R Centrifuge)


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