Tube holder for 0.65 ml tubes - Bioruptor® Pico. The tube holder for 0.65 ml tubes has been especially designed for being used with the Bioruptor® Pico and to guarantee homogeneity of chromatin and DNA shearing. It allows for reproducible sonication of up to 12 x 0.65 ml tubes at a time with a sample volume of 100 µl. The holder is made up of a tube holder and its specific dock that makes the sample preparation more ergonomic.