Oxygen is an important
aspect of the environment for cells in vitro. It affects the
differentiation and proliferation of cells as well as the expression of
many genes or regulators.
Oxygen incubators do
not have the range of oxygen concentration that cells need, such as 1.0%
or lower. If you need to only culture a few plates, an incubator is not
efficient. Flushboxes with premixed gas is a lot of work and gas levels
may be inconsistent over the course of the experiment
The OxC System
provides modular and scalable components to optimize your oxygen sensitive
research. The system can be configured for any diverse need and upgraded
at any time. Whether you are just starting oxygen sensitive research or
are a veteran, we will build a system to fit your needs.
The OxC system is the most efficient,
definitive and flexible system for oxygen cell culture research. It
combines all the components, controllers to chambers, and fits them to
your needs.
Controllers are
definitive and precise because they work by feedback control. As soon as
the oxygen level is disrupted, the sensor catches the change and the
controller immediately reacts to bring the concentration back to setpoint.
Regardless of chamber leaks, oxygen consumption or generation within the
chamber, the controllers efficiently keep the chamber at setpoint.
Chambers sit inside
the host incubator and serve as an atmosphere for your cultures. The
chambers come in several sizes to maximize the controllers' efficiency.
Using the smallest chamber needed is the best option because you consume
less gas, use less space in host incubator and the chamber reaches the
setpoint faster.
The OxC System is
flexible and scalable to fit your needs. There are various options
available from single setpoint control to profiling and dissolved oxygen
monitoring. It can be configured for any diverse need. An extensive
upgrade path has been designed from the start.
The ProOxC system is
the simplest OxC system. It is a single setpoint, single chamber,
normobaric oxygen controller. Our C-Chambers are designed to work
efficiently with the ProOx controller.
The ProOx is small in
size and takes up little lab space. The C-Chamber sits inside your host
incubator and is connected to the ProOx by a tiny umbilical, which can be
threaded into the incubator through any port or passageway. The system is
compact and multiple chambers will fit inside most temperature controlled
incubators.
This system has
various options, such as dissolved oxygen control or adding carbon dioxide
control with our ProCO2 controller. Multiple controllers allow you to
control in multiple chambers and each can have different oxygen levels.
The ProOxC system is
the starting point for the OxC system. Upgrades begin here.
The C42 System
includes our sophisticated OxyCycler controller as well as C- Chambers and
a computer interface system. This system allows you to perfectly simulate
dynamic physiologic conditions with control over oxygen and carbon dioxide
concentrations.
Our elite OxyCycler
controllers allow you to program oxygen and carbon dioxide concentrations
to change automatically over time. Setpoints can be anywhere from 0.1% to
99.9% oxygen (0.0% to 20.0% CO2) and can be held for any length of time.
The rate of change between two setpoints is fully adjustable and any
profile can be cycled continuously or a fixed number of cycles.
This system has
various options similar to the ProOx/C system, such as dissolved oxygen
control. Never again assume what level of oxygen your cells see; control
and document oxygen levels within the media.
The C42 System
includes two of our C-Chambers, but has options for multiple chambers. The
controller simultaneously controls different profiles in different
chambers.
The computer interface
allows real-time trend charting, data logging and remote operation.
The OxC System is
designed for uninterruptible oxygen control. The C-Shuttle Glovebox system
provides an oxygen-controlled environment for handling cells. Whether your
controlling with the ProOx or the C42, the C-Shuttle is a separate option
for uninterrupted oxygen control.
The C-Chambers provide
a gas tight transport chamber from your incubator to the C-Shuttle.
The C-Shuttle has
options for housing the C-Chambers within an incubator inside the glovebox.
The OxC System is
completely flexible and customizable. We build all of the components you
need for your oxygen sensitive research. They are all integrated and
modular so as your needs change, the equipment adapts to your needs. Any
configuration is possible and you have complete flexibility. No other
system compares for efficient, definitive, oxygen research.
